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IGF-1 LR3

Third-Party Tested · COA Available

IGF-1 LR3 1 mg is a synthetic IGF-1 analog used in laboratory research for somatomedin signaling and IGF-1 receptor interaction studies. HPLC-purified for high analytical purity, it is suitable for investigating peptide-receptor activity and biochemical mechanisms.

  • 99.9% Purity
  • Research Grade
  • COA Verified
  • Third-Party Tested
$85.00 / 1 mg · USD
Volume pricingApplied automatically at checkout
QuantityPer unitYou save
3–4 units$79.057%
5–9 units$75.6511%
10+ units$71.4016%
Add 2 more to save 7% on every unit.
1
SKU IGF-1-LR3-1MG
  • Certificate of Analysis available for every lot
  • ≥99% purity, HPLC & mass-spec verified
  • Ships from a U.S. facility — same-day before 12pm CT
  • Secure checkout · Free shipping on orders $300+

Synthetic Peptide for Growth Factor Research

Technical Overview

IGF-1 LR3 1mg is a synthetic peptide compound developed for laboratory research involving insulin-like growth factor signaling and somatomedin pathway analysis, receptor interaction analysis, and controlled experimental investigation. In research settings, this peptide is commonly utilized for studying IGF-1 receptor activation profiles, PI3K/Akt and MAPK pathway dynamics, and related biochemical mechanisms.

IGF-1 LR3 is a recombinant 83-residue IGF-1 analog with arginine substituted for glutamic acid at position 3 and an additional 13-residue N-terminal extension. These modifications dramatically reduce binding to IGF binding proteins (IGFBP-1 through IGFBP-6), increasing the proportion of bioavailable peptide for receptor interaction in cell-culture systems.

Researchers utilize this analog to study cell-cycle progression, protein synthesis, and survival signaling in myoblast, hepatocyte, and stem-cell models. Its reduced IGFBP affinity makes it a preferred tool for distinguishing receptor-mediated effects from binding-protein-mediated sequestration.

This compound is synthesized using established solid-phase peptide synthesis methods and purified through reversed-phase HPLC to achieve analytical purity suitable for laboratory assays, binding studies, and analytical applications. The lyophilized material is supplied for reconstitution per established laboratory protocols and is intended as a reference material in controlled research environments.

Specifications

Compound Name: IGF-1 LR3
Strength: 1mg
Purity: ≥ 99% (HPLC Verified)
Appearance: Lyophilized Peptide Powder
Format: Research Compound
Reconstitution: Suitable for laboratory assay preparation.

Notice

Provided as a reference material for scientific investigation only.

Purity≥99% by HPLC · COA available
CAS Number946870-92-4
Molecular FormulaC400H625N111O115S9
Molecular Weight9117.60
Amino Acid Count83
Sequence83-residue recombinant IGF-1 analog with Arg substituted for Glu at position 3 and a 13-residue N-terminal extension; modifications reduce IGFBP affinity and extend circulating half-life relative to native IGF-1 (full sequence per COA).
SynonymsLong R3 Insulin-like Growth Factor-1
Physical FormLyophilized powder
SolubilitySoluble in bacteriostatic water; consult the product COA for specific solvent recommendations.
StorageStore lyophilized at -20°C; protect from light and moisture. Reconstitute with bacteriostatic water; store reconstituted material refrigerated and use per laboratory protocol.
Documentation

Certificate of Analysis & Safety Data

Answers

Frequently Asked Questions

Is IGF-1 LR3 third-party tested?

Yes. Every lot is independently third-party tested for identity and purity — ≥99% by HPLC and mass spectrometry — with a lot-matched Certificate of Analysis available to download on this page.

Can I see the Certificate of Analysis before buying?

Yes. A lot-matched COA is available on this product page and in our COA library before purchase, documenting identity, purity, and full analytical results.

What does 'Research Use Only' mean?

This product is supplied strictly for laboratory and research use only (RUO). It is not a drug, food, supplement, or cosmetic, is not approved by the FDA, and is not intended to diagnose, treat, cure, or prevent any disease, or for human or veterinary consumption.

How is it shipped and stored?

Orders placed before 12pm CT typically ship the same business day from our U.S. facility with tracking. Store the lyophilized material at −20°C, protected from light and moisture.

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