PT-141
Third-Party Tested · COA AvailablePT-141 10 mg is a synthetic cyclic heptapeptide used in laboratory research for melanocortin receptor signaling and binding studies. HPLC-purified for high analytical purity, it is suitable for investigating peptide-receptor activity and biochemical mechanisms.
- 99.9% Purity
- Research Grade
- COA Verified
- Third-Party Tested
- Certificate of Analysis available for every lot
- ≥99% purity, HPLC & mass-spec verified
- Ships from a U.S. facility — same-day before 12pm CT
- Secure checkout · Free shipping on orders $300+
Synthetic Peptide for Melanocortin Receptor Research
Technical Overview
PT-141 10mg is a synthetic peptide compound developed for laboratory research involving melanocortin signaling and central neuroendocrine pathways, receptor interaction analysis, and controlled experimental investigation. In research settings, this peptide is commonly utilized for studying MC3R and MC4R receptor binding, downstream cAMP signaling in hypothalamic models, and related biochemical mechanisms.
PT-141 (bremelanotide) is a cyclic heptapeptide analog of alpha-melanocyte-stimulating hormone (alpha-MSH) featuring a side-chain lactam bridge between Asp and Lys, N-terminal acetylation, and incorporation of norleucine and D-phenylalanine for protease resistance. It is a non-selective agonist of MC1R, MC3R, MC4R, and MC5R with preferential activity at MC3R/MC4R.
Researchers use PT-141 to investigate central melanocortin signaling, sexual-behavior circuits in rodent models, and receptor-selectivity comparisons against alpha-MSH and NDP-MSH. Its protease-resistant structure makes it a stable reference compound for melanocortin receptor pharmacology.
This compound is synthesized using established solid-phase peptide synthesis methods and purified through reversed-phase HPLC to achieve analytical purity suitable for laboratory assays, binding studies, and analytical applications. The lyophilized material is supplied for reconstitution per established laboratory protocols and is intended as a reference material in controlled research environments.
Specifications
Compound Name: PT-141
Strength: 10mg
Purity: ≥ 99% (HPLC Verified)
Appearance: Lyophilized Peptide Powder
Format: Research Compound
Reconstitution: Suitable for laboratory assay preparation.
Notice
Provided as a reference material for scientific investigation only.
Certificate of Analysis & Safety Data
Frequently Asked Questions
Is PT-141 third-party tested?
Yes. Every lot is independently third-party tested for identity and purity — ≥99% by HPLC and mass spectrometry — with a lot-matched Certificate of Analysis available to download on this page.
Can I see the Certificate of Analysis before buying?
Yes. A lot-matched COA is available on this product page and in our COA library before purchase, documenting identity, purity, and full analytical results.
What does 'Research Use Only' mean?
This product is supplied strictly for laboratory and research use only (RUO). It is not a drug, food, supplement, or cosmetic, is not approved by the FDA, and is not intended to diagnose, treat, cure, or prevent any disease, or for human or veterinary consumption.
How is it shipped and stored?
Orders placed before 12pm CT typically ship the same business day from our U.S. facility with tracking. Store the lyophilized material at −20°C, protected from light and moisture.
